Effects of modulation defects on hadamard transform time-of-flight mass spectrometry (HT-TOFMS)
نویسندگان
چکیده
منابع مشابه
Effects of modulation defects on Hadamard transform time-of-flight mass spectrometry (HT-TOFMS).
In any Hadamard multiplexing technique, discrepancies between the intended and the applied encoding sequences may reduce the intensity of real spectral features and create discrete, artificial signals. In our implementation of Hadamard transform time-of-flight mass spectrometry (HT-TOFMS), the encoding sequence is applied to the ion beam by means of an interleaved comb of wires (Bradbury-Nielso...
متن کاملHadamard Transform Time-of-Flight Mass Spectrometry
A new mode of operation of a time-of-flight mass spectrometer (TOFMS) is described and demonstrated. A continuous ion beam emerging from the ion source is accelerated and then modulated by a pseudorandom sequence of “on” and “off” pulses. The data acquisition period is set to match the period of the modulation sequence, and data are acquired synchronously with the modulation of the ion beam. Th...
متن کاملDuty cycle and modulation efficiency of two-channel Hadamard transform time-of-flight mass spectrometry.
Hadamard transform time-of-flight mass spectrometry (HT-TOFMS) is based on the pseudorandom gating of ion packets into a time-of-flight mass-to-charge analyzer. In its typical implementation, the technique is able to monitor continuous ion sources with a 50% duty cycle, independent of all other figures of merit. Recently, we have demonstrated that the duty cycle can be extended to 100% using pa...
متن کاملHadamard transform time-of-flight mass spectrometry: more signal, more of the time.
Hadamard transform time-of-flight mass spectrometry (HT-TOF MS) is a type of mass analysis that was developed to couple continuous ion sources to the inherently pulsed nature of time-of-flight measurements. Unlike conventional TOF MS, the Hadamard transform method offers a duty cycle of 50%, with the possibility of extending it to 100%. Because it is a multiplexing technique, the attainable sig...
متن کاملApplication of Hadamard transform to gas chromatography/nonresonant multiphoton ionization/time-of-flight mass spectrometry.
The technique of Hadamard transform was successfully coupled with GC/nonresonant multiphoton ionization/TOFMS, for the first time. 1,4-Dichlorobenzene and the fourth harmonic generation (266 nm) of a Nd:YAG laser were employed as a model sample and an ionization laser, respectively. A Hadamard-injector coupled with a capillary-based supersonic jet nozzle (capillary-injector) was also developed ...
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ژورنال
عنوان ژورنال: Journal of the American Society for Mass Spectrometry
سال: 2003
ISSN: 1044-0305,1879-1123
DOI: 10.1016/s1044-0305(03)00006-0